Breast Cancer Risk Assessment

Estimating the risk of breast cancer involves reviewing how many risk factors a patient has and how much each of these factors increase breast cancer risk. Exactly which risk factors should be used is still being studied, and there are currently several models that are being utilized for this purpose.

There are multiple breast cancer risk models but none are ideal. Each model uses different groups of presumed breast cancer risk factors to estimate the risk of breast cancer, and results may vary from model to model due to differences in the factors taken in to account. The factors fall in three basic categories: hereditary, hormonal, and pathologic. The risk of breast cancer over time can help provide guidance for different management plans such as earlier (or later) mammography, risk-based screening, adding MRI, or the need for chemoprevention. The risk of mutation can help determine the need for genetic testing.

EVDI includes calculations for several risk models in our radiology reports to give you a better idea of a patient’s 5-year and lifetime breast cancer risk. The graphic shows a quick snapshot of the thresholds for each of these models, and each model is explained in further detail by clicking the model name below.

Tyrer-Cusik 10 Year & Lifetime Models

Myriad BRCA Prevalence Table

Gail 5 Year & NCI Lifetime Models

For more information and recommendations on what exams are appropriate for a patient’s risk level, please see our links to Recommendations for Early Breast Cancer Detection